Diabetes Research and Clinical Practice - Volume 120 - Supplement 1

therapy. Clinically, there are patients with T2DM whose

aerobic capacity is preserved and thosewhose aerobic capacity

is not preserved. However, no studies have assessed the factor

of aerobic fitness.

Purpose:

The purpose of this study was to examine the

characteristic differences between patients with T2DM

whose ATVO2 was normal and those whose ATVO2 was low.

Method:

Forty-six patients with T2DM (mean age: 43.9 ± 6.2

years, mean HbA1c: 10.3 ± 2.4%) underwent expiratory gas

analysis while performing incremental exercise test on a cycle

ergometer 3 h after eating. The ramp protocol (20 W/min)

was used. VO2, carbon dioxide output (VCO2), and maximum

lipid oxidation were measured during the exercise test. The

amount of lipid oxidation (g/min) during exercise was

calculated using the Bruzstein formula. AT was evaluated as

ventilation threshold using the V-slope method. ATVO2 was

compared with the standard value of the Japanese Circulation

Association. The subjects were divided into two groups based

on normal or low ATVO2. Normal and low AT groups were

defined as ATVO2 higher than 90% and lower than 90% of the

standard value, respectively. We compared the body mass

index (BMI), HbA1c, fasting plasma glucose, skeletal muscle

and fat amount, visceral fat sectional area, maximum lipid

oxidation amount, and respiratory quotient at rest between

normal and low AT groups using t-test or Mann

–

Whitney U

test. A software package (IBM SPSS Statistics Version 22) was

used with a significance level at <5% for statistical analysis.

Result:

The normal and low AT groups had 15 and 31 patients,

respectively. The following characteristics were observed in

patients in the normal AT group as compared with those in the

low AT group with statistically significant difference: lower

BMI (p < 0.01), lower skeletal muscle amount (p = 0.02), higher

fat amount (p < 0.01), lower visceral fat sectional area (p = 0.04),

and higher maximum amount of lipid oxidation (p < 0.01).

Conclusion:

In patients with T2DM, high BMI, high fat amount,

and low lipid oxidation at exercise decreased aerobic fitness. It

is suggested that aerobic fitness in patients with T2DM is

determined by lipid metabolism.

PF-18

The association between self-reported sleep quality and

arterial stiffness

Ching-Han LIN

, Hao-Chang HUNG

, Jin-Shang WU

Chih-Jen CHANG

Division of Endocrinology and Metabolism,

Department of Internal Medicine, National Cheng Kung University

Hospital,

Department of Family Medicine, National Cheng Kung

University Hospital, Taiwan

Sleep has a major role in maintaining health, and is

involved in the regulation of metabolism, vascular and

autonomic nervous functions. Short and long sleep duration,

and poor sleep quality are associated with an increased risk

of cardiovascular disease (CVD). In addition, epidemiologic

studies show that poor sleep quality is associated with

cardiovascular risk factors, such as diabetes, obesity, and

metabolic syndrome. Furthermore, poor sleep quality without

change in total sleep time lead to insulin resistance and

increased sympathoadrenal activity.

Arterial stiffness, a decrease in the compliance of the central

arterial system, is recognized a surrogate marker for cardio-

vascular disease. Apart from ageing, many pathophysiological

conditions are associated with increased arterial stiffness,

such as hypertension, diabetes, obesity, hyperlipidemia,

smoking, and metabolic syndrome. In addition, previous

studies suggest that insulin resistance is associated with

arterial stiffness. Although sleep quality and arterial stiffness

are both associated with insulin resistance, their interactions

have not been clarified. Therefore, the aim of this study is to

investigate the association between sleep quality and arterial

stiffness.

Cross-sectional data were collected from a decoded

database of the National Cheng Kung University. Subjects

with history of hypertension, diabetes, coronary heart disease,

old stroke, peripheral atherosclerosis with an ankle-brachial

index less than 0.95, amputation of either lower limb, alcohol

consumption of greater than 30 g/wk, and those taking

medications influencing blood pressure, plasma glucose, and

lipid profile were excluded. Hospital. Sleep quality was

measured using the Pittsburgh Sleep Quality Index (PSQI).

Arterial stiffness was measured by brachial-ankle pulse wave

velocity (baPWV).

Of the total 400 participants enrolled, 200 were poor

sleepers (PSQI > 5) and 200 were good sleepers (PSQI

≤

5). Poor

sleepers had significantly higher baPWV, systolic blood

pressure (SBP), diastolic blood pressure (DBP), and prevalence

of hypertension than those of good sleepers. The multivariate

logistic regression analysis showed that age, baPWV, and

snoring were independent determinants of being poor slee-

pers after adjusting for gender, body mass index (BMI), SBP,

fasting plasma glucose, creatinine, lipid profile, alcohol

drinking, tea and coffee consumption, smoking habit, and

habitual exercise.

Poor sleepers had a significantly higher baPWV value than

those of good sleepers. Furthermore, age and baPWV were

associated with being poor sleepers independently of cardio-

metaolic risk factors. In clinical practice, subjects who

complain sleep disturbance should be evaluated for the

presence of cardiometabolic risk factors, including baPWV.

PF-19

The applicability research of portion-controlled tableware

developed by Taiwanese Association of Diabetes Educators in

common Chinese food

Ti Yung CHANG

, Shiow-Miaw YIN

, Frances Chang MA

Shih-Tzer TSAI

Department of Nutrition, Cheng-Hsin General

Hospital,

Enjoy Foods Nutrition Center,

Department of Internal

Medicine, Cheng-Hsin General Hospital, Taiwan

Background and aims:

In 2013, Taiwanese Association of

Diabetes Educators (TADE) developed a set of portion-con-

trolled tableware for diabetes who need diet control to achieve

their goals. In this research, we investigated the applicability of

this tableware for common Chinese food.

Method:

We chose common Chinese food in different categor-

ies including staples, meat and vegetables from the menu

which provided for hospitalized patients in Chen-Hsin

Hospital and served them with the TADE portion-controlled

tableware according to its instructions. We investigated the

quantitative rules of dish arrangements by elaborating the

quantitative functions and visual impression.

Results:

The scales labeled on the bowl are accurate for staples,

such as rice, gruel and noodles. Food cut into small cubes or

grounded meat was easy to fill the oval-shaped sections and

facilitating for portion estimation. We modified the quantita-

tive instructions of TADE plate when we encountered mix-

meat-vegetable dishes and ingredients with loose compos-

ition which often seen in Chinese food services, such us fired

eggwithmeat, steamed egg and dried fish floss, and re-defined

a portion filling one small section of the TADE plate as 0.5

instead of 1 exchange of soybeans, meat and eggs. When meat

served with larger portion such as chicken leg or pork chops,

we suggest to place them in another container and defined as

2 exhange of meat.

Conclusion:

By demonstrating more ways to arrange dishes

and providing quantitative rules will enhance the practicality

of applying TADE tableware. Furthermore, this TADE tableware

is appropriate not only for diabetic portion teaching but also

for personal use at home.

Poster Presentations / Diabetes Research and Clinical Practice 120S1 (2016) S65

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